recombinant human ctrp3 rhctrp3 Search Results


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R&D Systems recombinant human ctrp3 rhctrp3
(A) Representative whole-femur μCT isosurface renderings at 5, 10 and 20dpf for <t>CTRP3</t> KO, WT and TG mice. Femurs were scanned after removal of intramedullary pins. Apparent bends in 5dpf bones are artifacts of this removal: fractures are straight in vivo. Quantitative callus μCT data for (B) bone volume fraction (BV/TV), (C) bone mineral content (BMC) and (D) bone mineral density (BMD). Solid lines represent p<0.05 by genotype. Maroon up-arrows represent female mice and navy down-arrows represent male mice. For additional quantitative measures of calluses, see Fig S1.
Recombinant Human Ctrp3 Rhctrp3, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
recombinant human ctrp3 rhctrp3 - by Bioz Stars, 2026-07
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Image Search Results


(A) Representative whole-femur μCT isosurface renderings at 5, 10 and 20dpf for CTRP3 KO, WT and TG mice. Femurs were scanned after removal of intramedullary pins. Apparent bends in 5dpf bones are artifacts of this removal: fractures are straight in vivo. Quantitative callus μCT data for (B) bone volume fraction (BV/TV), (C) bone mineral content (BMC) and (D) bone mineral density (BMD). Solid lines represent p<0.05 by genotype. Maroon up-arrows represent female mice and navy down-arrows represent male mice. For additional quantitative measures of calluses, see Fig S1.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Article Title: CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing

doi: 10.1002/jor.24553

Figure Lengend Snippet: (A) Representative whole-femur μCT isosurface renderings at 5, 10 and 20dpf for CTRP3 KO, WT and TG mice. Femurs were scanned after removal of intramedullary pins. Apparent bends in 5dpf bones are artifacts of this removal: fractures are straight in vivo. Quantitative callus μCT data for (B) bone volume fraction (BV/TV), (C) bone mineral content (BMC) and (D) bone mineral density (BMD). Solid lines represent p<0.05 by genotype. Maroon up-arrows represent female mice and navy down-arrows represent male mice. For additional quantitative measures of calluses, see Fig S1.

Article Snippet: The fracture procedure was then repeated in WT mice aged 34±3 weeks to test a systemic protein delivery strategy; animals in this cohort received either phosphate buffered saline (PBS) vehicle (Vh) or 5.0μg recombinant human CTRP3 (rhCTRP3) (R&D Systems, produced in mouse NS0 cells) in PBS and harvested at 21dpf.

Techniques: In Vivo

Safranin-O micrographs from CTRP3 KO, WT and TG mice at (A) 5dpf, (B) 10dpf and (C) 20dpf. Images are oriented to show one side of the callus in longitudinal section with cortical bone at the bottom (light blue staining). Three selected areas of callus (white squares) are magnified on the right of each panel. For associated histomorphometry, see Fig S2.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Article Title: CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing

doi: 10.1002/jor.24553

Figure Lengend Snippet: Safranin-O micrographs from CTRP3 KO, WT and TG mice at (A) 5dpf, (B) 10dpf and (C) 20dpf. Images are oriented to show one side of the callus in longitudinal section with cortical bone at the bottom (light blue staining). Three selected areas of callus (white squares) are magnified on the right of each panel. For associated histomorphometry, see Fig S2.

Article Snippet: The fracture procedure was then repeated in WT mice aged 34±3 weeks to test a systemic protein delivery strategy; animals in this cohort received either phosphate buffered saline (PBS) vehicle (Vh) or 5.0μg recombinant human CTRP3 (rhCTRP3) (R&D Systems, produced in mouse NS0 cells) in PBS and harvested at 21dpf.

Techniques: Staining

Whole-callus mRNA expression of (A) CTRP3, (B) α-actin-2 (ACTA2), (C) osterix (SP7), (D) collagen-II (COL2A1) and (E) tartrate-resistant acid phosphatase (TRAP) vary based on CTRP3 genotype. Relative expression is presented at 2−dCt with ACTB as a housekeeping gene. Statistics were run on dCt values. Solid lines represent p<0.05 by genotype. Maroon up-arrows represent female mice and navy down-arrows represent male mice.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Article Title: CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing

doi: 10.1002/jor.24553

Figure Lengend Snippet: Whole-callus mRNA expression of (A) CTRP3, (B) α-actin-2 (ACTA2), (C) osterix (SP7), (D) collagen-II (COL2A1) and (E) tartrate-resistant acid phosphatase (TRAP) vary based on CTRP3 genotype. Relative expression is presented at 2−dCt with ACTB as a housekeeping gene. Statistics were run on dCt values. Solid lines represent p<0.05 by genotype. Maroon up-arrows represent female mice and navy down-arrows represent male mice.

Article Snippet: The fracture procedure was then repeated in WT mice aged 34±3 weeks to test a systemic protein delivery strategy; animals in this cohort received either phosphate buffered saline (PBS) vehicle (Vh) or 5.0μg recombinant human CTRP3 (rhCTRP3) (R&D Systems, produced in mouse NS0 cells) in PBS and harvested at 21dpf.

Techniques: Expressing

μCT (A) quantitation and (B) isosurface renderings at 21dpf in mice that received either subcutaneous Vh or 5μg rhCTRP3 protein at time of surgery. Outputs include total volume (TV), bone volume (BV), bone volume fraction (BV/TV), bone mineral content (BMC), bone mineral density (BMD), tissue mineral content (TMC) and tissue mineral density (TMD). Maroon up-arrows represent female mice and navy down-arrows represent male mice.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Article Title: CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing

doi: 10.1002/jor.24553

Figure Lengend Snippet: μCT (A) quantitation and (B) isosurface renderings at 21dpf in mice that received either subcutaneous Vh or 5μg rhCTRP3 protein at time of surgery. Outputs include total volume (TV), bone volume (BV), bone volume fraction (BV/TV), bone mineral content (BMC), bone mineral density (BMD), tissue mineral content (TMC) and tissue mineral density (TMD). Maroon up-arrows represent female mice and navy down-arrows represent male mice.

Article Snippet: The fracture procedure was then repeated in WT mice aged 34±3 weeks to test a systemic protein delivery strategy; animals in this cohort received either phosphate buffered saline (PBS) vehicle (Vh) or 5.0μg recombinant human CTRP3 (rhCTRP3) (R&D Systems, produced in mouse NS0 cells) in PBS and harvested at 21dpf.

Techniques: Quantitation Assay